Transaction Case Studies
Agreement to Develop and Commercialize Tecarfarin in Greater China and Thailand
Situation Assessment
- Armetheon is a private, specialty pharmaceutical company which is developing a late-stage cardiovascular asset:
- Tecarfarin a novel, oral anti-coagulant to treat patients with prosthetic heart valves and other conditions requiring the use of an anticoagulant
- The company was founded by three entrepreneurs with intimate knowledge of Tecarfarin, who identified a new strategic approach that would better position Tecarfarin in the anticoagulant market
- Armetheon engaged Locust Walk’s Asia Team to identify an ideal partner for Greater China, negotiate the term sheet, and execute a definitive License Agreement
Key Activities
Through its Asia team, Locust Walk pursued multiple work streams to successfully close a strategic partnership for Armetheon in Greater China:
- Locust Walk carried out quantitative research to over 130 physicians in the People’s Republic of China, the results of which were used to craft the Tecarfarin story for potential partners
- Locust Walk participated in qualitative interviews with key opinion leaders at large cardiovascular hospitals in Beijing
- Through its c-level contacts, Locust Walk introduced Armetheon to Lee’s Pharmaceutical in 2014 as a potential partner for Tecarfarin in Greater China
- Locust Walk managed the negotiations that led to agreement on basic terms between Armetheon and Lee’s, and led negotiations on the definitive License Agreement
Successful Outcome
- In 1Q 2015, Lee’s became an investor in Armetheon through its participation in Armetheon’s $24M Series B round
- In September 2015, Armetheon and Lee’s signed an agreement granting Lee’s the exclusive right to develop and commercialize Tecarfarin in the People’s Republic of China, Hong Kong, Macau, Taiwan and Thailand
- Substantial deal economics relative to traditional Greater China deals, including an upfront payment, Lee’s investment in Armetheon, development and commercial milestones