Biopharma
Biopharma Market Dynamics and Challenges
Moving into 2021, the current market conditions indicate continued optimism for early stage and growth biopharma companies following a record year for private financings across the US, Europe and Asia. In the States, approval of two COVID-19 vaccines led biopharma indices and the S&P 500 to finish the year in an upswing. Across “the pond”, European biotech financings set a historical record in 2020 with no signs of slowing—considering Q4 had the highest volume to date—and were weighted more heavily towards earlier stage investments. Japan had another strong year in licensing and more noticeable in 2020 was the volume and total size of venture financing, which vastly surpassed the previous record set in 2018. And, China continued its torrid pace of in-licensing deals, featuring transactions with substantial size, including 6 deals with upfront payment of $30M and above.
Enter Locust Walk
For many emerging biopharma companies that need to raise capital via strategic partnerships or equity financings, we supplement a company’s C-suite or existing BD team with an expanded reach of capabilities, key contacts and long-standing relationships.
Locust Walk provides emerging biopharma companies with the strategic guidance and resources required to achieve their milestones and fulfill their potential. Since we don’t have the day-to-day pressures of managing a biopharma company, we can maintain a singular focus on helping to set strategy and then executing against the plan to deliver results for you regardless of the geographic focus of your deal.
Growth-oriented companies are often pursued as acquisition targets of other companies. Their best defense: Increasing scale and market valuation to stay beyond the reach of potential suitors and remain independent. For those that ultimately are acquired, on clinical and commercial capabilities and pipeline can often increase deal value. On the buy-side, most late-stage companies are looking to accelerate growth by bringing in additional clinical or commercial products.
Locust Walk is a market-maker with the ability to identify—uncovering overlooked assets—and transact target assets and companies across geographies, therapeutic areas, and modalities. Our comprehensive global footprint also enables the team to find assets wherever they reside. Strategic deals and transactions can help enable a company to go public, get to a commercial stage more quickly, fill a critical pipeline gap, or simply add another product to a sales rep’s “bag” to complement existing marketed products.
Locust Walk provides exciting new companies with the guidance and resources required to hit strategic growth benchmarks and fulfill their technological and market potential.
Our team’s deep industry experience enables us to help emerging biopharma firms scale up through rigorous assessment and analysis, connectivity with funding sources and strategic partners, and hands-on operational support.




Business & Corporate Development
Financing & IPO Advisory
- Business case development
- Targeted partner outreach
- Due diligence staging
- Deal structuring and evaluation
- Contract negotiations
- Data-driven approach
- Structured process
- Competitive tension and bidding
- Real-time negotiations
- Maximum deal value
- Commercial assessment
- Investor materials preparation
- Targeted investor outreach
- Due diligence staging
- Deal comparables
- Introductions to bankers and research analysts
- S1 drafting (business section)
- Robust understanding of opportunity
- Succinct presentations
- Relevant Investors
- Competitive process
- Realistic valuation and optimal outcome
Locust Walk offers a unique blend of exclusivity, superior deal flow, depth of expertise, and breadth of service for the growth biopharma sector.
Our international team of seasoned industry executives delivers specific, relevant operating deal experience. We provide comprehensive and exclusive guidance and support on both the buy-side and the sell-side.




Buy-side Process
Sell-side Process
- Asset criteria development
- Opportunity screening
- Profile development
- Target outreach
- Due diligence
- Deal structuring and evaluation
- Contract negotiations
- Strategic fit
- Non-obvious opportunities
- Timely decision-making
- Transactability
- Immediate increase in shareholder value
- Business case development
- Targeted partner outreach
- Due diligence staging
- Deal structuring and evaluation
- Contract negotiations
- Data-driven approach
- Structured process
- Competitive tension and bidding
- Real-time negotiations
- Maximum deal value
Locust Walk provides exciting new companies with the guidance and resources required to hit strategic growth benchmarks and fulfill their technological and market potential.
Our team’s deep industry experience enables us to help emerging biopharma firms scale up through rigorous assessment and analysis, connectivity with funding sources and strategic partners, and hands-on operational support.

Business & Corporate Development
OVERVIEW
- Business case development
- Targeted partner outreach
- Due diligence staging
- Deal structuring and evaluation
- Contract negotiations

RESULTS
- Data-driven approach
- Structured process
- Competitive tension and bidding
- Real-time negotiations
- Maximum deal value

Financing & IPO Advisory
OVERVIEW
- Commercial assessment
- Investor materials preparation
- Targeted investor outreach
- Due diligence staging
- Deal comparables
- Introductions to bankers and research analysts
- S1 drafting (business section)

RESULTS
- Robust understanding of opportunity
- Succinct presentations
- Relevant Investors
- Competitive process
- Realistic valuation and optimal outcome
Biopharma Transaction Highlights

CLIENT: Thar Pharmaceuticals
TRANSACTION:
Multi-Track Sell-Side and Financing Engagement Leading to Acquisition

CLIENT: Fabrus
PARTNER: Senesco
TRANSACTION:
Merger between Fabrus and Senesco Technologies

CLIENT: Strategic Science & Technologies, LLC
PARTNER: Undisclosed
TRANSACTION:
Worldwide Licensing Agreement for IbuCream (topical ibuprofen)

CLIENT: Strategic Science & Technologies, LLC
PARTNER: Global OTC Player
TRANSACTION:
US Option Agreement for IbuCream (topical ibuprofen)

CLIENT: Ascenta
PARTNER: Debiopharm Group
TRANSACTION:
Worldwide Licensing Agreement for AT-406

CLIENT: Concordia Pharmaceuticals
PARTNER: Ono
TRANSACTION:
Licensing Agreement for Salirasib in Japan

CLIENT: Angiochem
PARTNER: Geron
TRANSACTION: Worldwide Licensing Agreement for ANG1005 and Research Collaboration for Telomerase

CLIENT: Synthetic Genomics
PARTNER: Novartis
TRANSACTION:
Advisor in Forming New Company Synthetic Genomics Vaccines Inc. and Advisor on Structuring

CLIENT: InterMune
PARTNER: Vidara
TRANSACTION:
Actimmune Product Divestiture for $55M upfront plus 2 year royalty