Locust Walk

Transaction Case Studies

Regional sell-side engagement for Pacira leading to an European partnership agreement with Molteni

Situation Assessment

  • Pacira is a U.S.-based pharmaceutical company focused on developing and commercializing innovative, non-opioid pain therapies.

  • Pacira’s lead product, EXPAREL (bupivacaine liposome injectable suspension), is a long-acting local analgesic for postsurgical pain management that uses Pacira’s multivesicular liposome technology to deliver bupivacaine over time.

  • Following an earlier partnering process that did not result in a regional license, Pacira engaged Locust Walk to re-engage the market and identify ex-US commercialization partner(s) for EXPAREL

  • Locust Walk ran a competitive process with over 100 parties and ultimately led to a closed transaction with Molteni for EU, United Kingdom and Switzerland

Key Activities

  • Created targeted marketing materials and executed a broad outreach campaign to 100+ global and regional partners

  • Offered strategic advice and senior-level connectivity that improved deal valuation and structure including navigating concerns around most-favored nation pricing implications

  • Performed qualitative and quantitative analyses assessing EXPAREL valuation in the region

  • Led negotiations on term sheets and deal documents, identifying essential business terms for deal success

  • Worked closely with Pacira management and developed strong relationship with Molteni to drive the transaction toward successful conclusion

Successful Outcome

  • Executed a comprehensive outreach process, resulting in multiple interested parties, and ultimately a closed transaction including upfront, sales milestones, transfer payments, and a royalty

  • Provided Pacira a strong regional partner to ensure the development and commercialization of EXPAREL in a key marketplace and further build asset and company value

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